Central topics of the research are modelling, simulation, and analysis in mechanobiology. Specific examples range from mechanics of cytoskeletal networks and single cells to structure formation in cell cultures.
Typical length scales in mechanobiology.
Methods
Modelling:
- Continuum models: reaction-diffusion systems, fluid dynamics, elasticity theory
- Multiscale analysis
- Homogenisation (Two-scale convergence, Gamma-convergence)
Simulation:
Analysis:
- Bifurcation theory
- Asymptotic analysis
Projects (single cells)
- Dynamics of active biomembranes
with M. Mercker and Dr. M. Weiss (since 2008) - Cell migration
with lab of Prof. J. Spatz (since 2007) - Mechanics of fibroblasts
with lab of Prof. J. Spatz (since 2007) - Mechanics of red blood cells
(since 2003)
Projects (cell cultures)
- Evagination and invagination
with A. Köhler, Ph. D., Dr. F. Rossetti and Dr. M. Zigman (since 2008, funded by HAW) - Salivary gland branching morphogenesis
with Prof. M. Larsen (since 2008, funded by NIDCR) - Lung branching morphogenesis
with Dr. T. Miura (2003-2006) - Pattern formation in bacterial cultures
with Prof. M. Matsushita (2002-2003)